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Kratom preparations contain several phytochemicals in varying ratios rendering their proper pharmacological evaluation difficult. Human clinical studies are scarce.
https://www.keepandshare.com/doc6/38716/fphar-12-726003-pdf-584k?da=yIt’s not known exactly what level of kratom is toxic in people, but as with pain medications and recreational drugs, it is possible to overdose on kratom.
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